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Report: Lung Cancer Cases Decrease, Risk Factors Still Persist


— January 9, 2025

Lung cancer deaths drop, but tobacco, pollution, asbestos risks persist globally.


Over the past three decades, deaths from lung cancer and related diseases have dropped in some of the world’s most populated countries, signaling progress in public health efforts. However, the decline doesn’t tell the whole story. Tobacco use, air pollution, and asbestos exposure remain serious threats, each playing a significant role in these diseases. A study led by researchers from the University of Miami’s Sylvester Comprehensive Cancer Center sheds new light on these issues and what needs to be done.

The research analyzed global data on tracheal, bronchial, and lung cancers. From 1990 to 2019, deaths from these cancers dropped by 8%, a promising sign of progress. Despite this improvement, tobacco use continues to drive the majority of cases, even as deaths linked to smoking fell slightly. In 1990, tobacco accounted for 72% of these deaths, compared to 66% in 2019. While some countries have made strides in reducing tobacco use, others, such as China and Indonesia, have seen tobacco-related deaths rise. Women globally also experienced a slight increase in tobacco-linked mortality, underscoring the need for ongoing prevention efforts.

Air pollution is another growing concern. Over the same period, deaths related to air pollution saw mixed trends. While overall pollution-related deaths decreased, those tied directly to fine particulate matter (PM2.5) rose by 11%. This type of pollution comes from sources like vehicle emissions, industrial activity, and the burning of solid waste. China’s rates are double the global average, but the problem is not limited to one region. In countries like India, burning solid waste remains a common practice, often due to limited awareness and resources for safer alternatives.

Report: Lung Cancer Cases Decrease, Risk Factors Still Persist
Photo to by Anna Tarazevich from Pexels

Asbestos exposure continues to present dangers, particularly in the United States, where asbestos-related lung cancer deaths are nearly twice the global average. Despite bans and restrictions in many countries, the legacy of past asbestos use remains a significant factor. The study highlights the need to address lingering exposure risks and better understand how asbestos contributes to lung cancer development.

This research also emphasizes the importance of adapting cancer screening methods. Current guidelines focus heavily on tobacco exposure, which may overlook other significant risks. Younger individuals, especially women, are being diagnosed with lung cancer at higher rates despite low tobacco use. These cases often go undetected until later stages, when treatment options are limited. Expanding screening criteria to include other risk factors, such as air pollution exposure or a family history of cancer, could lead to earlier diagnoses and better outcomes.

The findings highlight the need for global cooperation in tackling these issues. Stronger policies to reduce tobacco use, limit air pollution, and eliminate asbestos exposure are essential. In addition, raising public awareness about these risks, especially in low-resource settings, could make a significant difference. For example, educating communities about the dangers of burning solid waste and providing alternatives could help reduce exposure to harmful pollutants.

Further research is needed to explore how these risk factors interact with each other and with genetic factors to drive cancer development. A deeper understanding could lead to more effective treatments tailored to individual patients based on their unique risk profiles. Targeted therapies, which focus on specific molecular changes in cancer cells, hold promise for improving survival rates and quality of life for patients.

Although the study shows progress in reducing deaths, the road ahead is long. Public health campaigns, stricter regulations, and continued research are all needed to build on these gains. The fight against lung cancer requires not just medical advances but also social and environmental changes to reduce exposure to known risks. By addressing the root causes, there is hope for further reducing the burden of these deadly diseases in the years to come.

Sources:

Lung cancer deaths decrease globally but risk factors still persist

Evolving trends in lung cancer risk factors in the ten most populous countries: an analysis of data from the 2019 Global Burden of Disease Study

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